翻訳と辞書
Words near each other
・ Interleukin 1 family
・ Interleukin 1 receptor antagonist
・ Interleukin 1 receptor, type I
・ Interleukin 1 receptor, type II
・ Interleukin 10
・ Interleukin 10 receptor, alpha subunit
・ Interleukin 10 receptor, beta subunit
・ Interleukin 11
・ Interleukin 11 receptor alpha subunit
・ Interleukin 12
・ Interleukin 12 receptor, beta 1 subunit
・ Interleukin 12 receptor, beta 2 subunit
・ Interleukin 12 subunit beta
・ Interleukin 13
・ Interleukin 13 receptor, alpha 1
Interleukin 15
・ Interleukin 15 receptor, alpha subunit
・ Interleukin 16
・ Interleukin 17
・ Interleukin 18
・ Interleukin 19
・ Interleukin 2
・ Interleukin 20
・ Interleukin 20 receptor, alpha subunit
・ Interleukin 20 receptor, beta subunit
・ Interleukin 21
・ Interleukin 22
・ Interleukin 23
・ Interleukin 23 subunit alpha
・ Interleukin 24


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Interleukin 15 : ウィキペディア英語版
Interleukin 15

Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells.
== Expression ==

Interleukin - 15 (IL-15) was discovered in 1994 by two different laboratories, and characterized as T cell growth factor.〔 Together with interleukin 2 (IL-2), interleukin 4 (IL-4), interleukin 7 (IL-7), interleukin 9 (IL-9), granulocyte colony-stimulating factor (G-CSF), and granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-15 belongs to the four α-helix bundle family of cytokine.〔
IL-15 is constitutively expressed by a large number of cell types and tissues, including monocytes, macrophages, dendritic cells (DC), keratinocytes, fibroblasts and nerve cells. As a pleiotropic cytokine, it plays an important role in innate and adaptive immunity.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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